Moyamoya Syndrome
Moyamoya syndrome also called Moyamoya disease is an inherited disease of the cerebral vasculature with particular involvement of the circle of Willis and the arteries that feed it.
The blood vessels develop collateral circulation around the blocked vessels to compensate for the blockage, but the collateral vessels are small, weak, and prone to hemorrhage, aneurysm and thrombosis.
The disease causes constrictions primarily in the internal carotid artery, which travels from the neck up to the Circle of Willis inside the skull just under the brain. At the Circle of Willis, the internal carotid artery flows into the middle cerebral artery, which continues into the brain, and the anterior cerebral artery, which is part of the Circle of Willis. Moyamoya disease often extends to the middle and anterior cerebral arteries.
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